Sakamoto M, Murata Y, Tanaka D, Kakuchi Y, Okamoto T, Hazama D, Saito Y, Kotani T, Ohnishi H, Miyasaka M, Fujisawa M, Matozaki T. Anticancer efficiency of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages. Proc Natl Acad Sci USA 119 (1): e2109923118, 2022 [PubMed]
Jingu D, Iino M, Kawasaki J, Urano E, Kusakari S, Hayashi Y, Matozaki T, Ohnishi H. Protein tyrosine phosphatase Shp2 positively regulates cold stress-induced tyrosine phosphorylation of SIRPα in neurons. Biochem Biophys Res Commun 569: 72-78, 2021 [PubMed]
Watanabe M, Kaneko Y, Ohishi Y, Kinoshita M, Sakairi T, Ikeuchi H, Maeshima A, Saito Y, Ohnishi H, Nojima Y, Matozaki T, Hiromura K. Importance of methodology in the evaluation of renal mononuclear phagocytes and analysis of a model of experimental nephritis with Shp1 conditional knockout mice. Biochem Biophys Rep 22: 100741, 2020 [PubMed]
Nishimura T, Saito Y, Washio K, Komori S, Respatika D, Kotani T, Murata Y, Ohnishi H, Mizobuchi S, Matozaki T. SIRPα on CD11c+ cells induces Th17 cell differentiation and subsequent inflammation in the CNS in experimental autoimmune encephalomyelitis. Eur J Immunol 50(10): 1560-1570, 2020 [PubMed]
Sato-Hashimoto M, Nozu T, Toriba R, Horikoshi A, Akaike M, Kawamoto K, Hirose A, Hayashi Y, Nagai H, Shimizu W, Saiki A, Ishikawa T, Elhanbly R, Kotani T, Murata Y, Saito Y, Naruse M, Shibasaki K, Oldenborg P-A, Jung S, Matozaki T, Fukazawa Y, Ohnishi H. Microglial SIRPα regulates the emergence of CD11c+ microglia and demyelination damage in white matter. eLife 8: e42025, 2019 [PubMed]
Alkebsi L, Ohnishi H, Nakajima-Shimada J, Onizuka Y, Ideno Y, Sato Y, Hayashi K. Validation of the accuracy of self-reported ABO blood types in the Japan Nurses’ Health Study. Asian Pac J Cancer Prev 20 (3): 789-793, 2019 [PubMed]
Alkebsi L, Ideno Y, Lee JS, Suzuki S, Nakajima-Shimada J, Ohnishi H, Sato Y, Hayashi K. Gastroduodenal ulcers and ABO blood group: the Japan Nurses’ Health Study (JNHS). J Epidemiol 28(1):34-40, 2018 [PubMed]
Saito Y, Respatika D, Komori S, Washio K, Nishimura T, Kotani T, Murata Y, Okazawa H, Ohnishi H, Kaneko Y, Yui K, Yasutomo K, Nishigori C, Nojima Y, Matozaki T. SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen. Proc Natl Acad Sci USA 114(47):E10151-E10160, 2017 [PubMed]
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya EW, Hazama D, Washio K, Saito Y, Kotani T, Ohnishi H, Oldenborg P-A, Garcia NV, Miyasaka M, Ishikawa O, Kanai Y, Komori T., Matozaki T. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight 2 (1): e89140, 2017 [PubMed]
Sakakura K, Takahashi H, Kaira K, Toyoda M, Murata T, Ohnishi H, Oyama T, Chikamatsu K. Relationship between tumor-associated macrophage subsets and CD47 expression in squamous cell carcinoma of the head and neck in the tumor microenvironment. Lab Invest 96 (9): 994-1003, 2016 [PubMed]
Moriya M, Inoue S, Miyagawa-Tomita S, Nakashima Y, Oba D, Niihori T, Hashi M, Ohnishi H, Kure S, Matsubara Y, Aoki Y. Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype. Hum Mol Genet 24 (25): 7349-7360, 2015 [PubMed]
Murata Y, Kotani T, Supriatna Y, Kitamura Y, Imada S, Kawahara K, Nishio M, Daniwijaya EW, Sadakata H, Kusakari S, Mori M, Kanazawa Y, Saito Y, Okawa K, Takeda-Morishita M, Okazawa H, Ohnishi H, Azuma T, Suzuki A, Matozaki T. Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium Proc Natl Acad Sci USA 112 (31): E4264-4271, 2015 [PubMed]
Kusakari S, Saitow F, Ago Y, Shibasaki K, Sato-Hashimoto M, Matsuzaki Y, Kotani T, Murata Y, Hirai H, Matsuda T, Suzuki H, Matozaki T, Ohnishi H. Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice Mol Cell Biol 35 (9): 1557-1572, 2015 [PubMed]
Motegi S, Yokoyama Y, Ogino S, Yamada K, Uchiyama A, Takeuchi Y, Ohnishi H, Ishikawa O. Pathogenesis of multiple lentigines in LEOPARD syndrome with PTPN11 gene mutation Acta Derm Venereol 95 (8): 978-984, 2015 [PubMed]
Li XJ, Goodwin CB, Nabinger SC, Richine BM, Yang Z, Hanenberg H, Ohnishi H, Matozaki T, Feng GS, and Chan RJ. Protein tyrosine phosphatase, Shp2, positively regulates macrophage oxidative burst J Biol Chem 290 (7): 3894-3909, 2015 [PubMed]
Washio K, Kotani T, Saito Y, Respatika D, Murata Y, Kaneko Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C, Matozaki T. Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs Genes Cells 20 (6): 451-463, 2015 [PubMed]
Yamashita H, Kotani T, Park JH, Murata Y, Okazawa H, Ohnishi H, Ku Y, Matozaki T. Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium PLoS One 9(3): e92904. 2014 [PubMed]
Murata Y, Kotani T, Ohnishi H, Matozaki T. The CD47-SIRPα signaling system: its physiological roles and therapeutic application J Biochem 155(6), 335-344, 2014 [PubMed]
Koshimizu H, Takao K, Matozaki T, Ohnishi H, Miyakawa T. Comprehensive behavioral analysis of Cluster of Differentiation 47 knockout mice PLoS ONE 9(2): e89584. 2014 [PubMed]
Murata Y, Saito Y, Kaneko T, Kotani T, Kaneko Y, Ohnishi H, Matozaki T. Autoimmune animal models in the analysis of the CD47-SIRPα signaling pathway Methods 65, 254-259, 2014 [PubMed]
Mantilidewi KI, Murata Y, Mori M, Otsubo C, Kotani T, Kusakari S, Ohnishi H, Matozaki T. Shear stress-induced redistribution of Vascular Endothelial-Protein Tyrosine Phosphatase (VE-PTP) in endothelial cells and its role in cell elongation J Biol Chem 289(19), 6451-6461, 2014 [PubMed]
Zen K, Guo Y, Bian Z, Lv Z, Zhu D, Ohnishi H, Matozaki T, Liu Y. Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state Nat. Commun. 4, 2436, 2013 [PubMed]
Takahashi S, Tomioka M, Hiromura K, Sakairi T, Hamatani H, Watanabe M, Ikeuchi H, Kaneko Y, Maeshima A, Aoki T, Ohnishi H, Matozaki T, Nojima Y. SIRPα signaling regulates podocyte structure and function Am J Physiol Renal Physiol 305(6), F861-870, 2013 [PubMed]
Hayashi Y, Kusakari S, Sato-Hashimoto M, Urano E, Shigeno M, Sekijima T, Kotani T, Murata Y, Murakami H, Matozaki T, Ohnishi H. Hypothermia-dependent and -independent effects of forced swim on the phosphorylation states of signaling molecules in mouse hippocampus Biochem Biophys Res Commun 428, 475-481, 2012 [PubMed]
Maruyama T, Kusakari S, Sato-Hashimoto M, Hayashi Y, Kotani T, Murata Y, Okazawa H, Oldenborg P-A, Kishi S, Matozaki T, Ohnishi H. Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain J Neurochem 121, 891-902, 2012 [PubMed]
Kaneko T, Saito Y, Kotani T, Okazawa H, Iwamura H, Sato-Hashimoto M, Kanazawa Y, Takahashi S, Hiromura K, Kusakari S, Kaneko Y, Murata Y, Ohnishi H, Nojima Y, Takagishi K, Matozaki T. Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity J Immunol 188, 5397-5407, 2012 [PubMed]
Nakakura T, Mogi C, Tobo M, Tomura H, Sato K, Kobayashi M, Ohnishi H, Tanaka S, Wayama M, Sugiyama T, Kitamura T, Harada A, Okajima F. Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin secretion Endocrinology 153, 4171-4180, 2012 [PubMed]
Wang L, Lu Y, Deng S, Zhang Y, Yang L, Guan Y, Matozaki T, Ohnishi H, Jiang H, Li H. SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress J Neurochem 122, 834-843, 2012 [PubMed]
Ohnishi H, Murata Y, Okazawa H, Matozaki T. Src family kinases: modulators of neurotransmitter receptor function and behavior Trends Neurosci. 34, 629-637, 2011 [PubMed]
Sato-Hashimoto M, Saito Y, Ohnishi H, Iwamura H, Kanazawa Y, Kaneko T, Kusakari S, Kotani T, Mori M, Murata Y, Okazawa H, Ware CF, Oldenborg P-A, Nojima Y, Matozaki T. Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen J Immunol 187, 291-297, 2011 [PubMed]
Iwamura H, Saito Y, Sato-Hashimoto M, Ohnishi H, Murata Y, Okazawa H, Kanazawa Y, Kaneko T, Kusakari S, Kotani T, Nojima Y, Matozaki T. Essential roles of SIRPα in homeostatic regulation of skin dendritic cells Immunol Lett 135, 100-107, 2011 [PubMed]
Kanazawa Y, Sato Y, Supriatna Y, Tezuka H., Kotani T., Murata Y., Okazawa H., Ohnishi H., Kinouchi Y., Nojima Y., Ohteki T., Shimosegawa T., Matozaki T. Role of SIRPα in regulation of mucosal immunity in the intestine Genes Cells 15, 1189-1200, 2010 [PubMed]
Morimoto N, Murata Y, Motegi S, Suzue K, Saito Y, Okazawa H, Ohnishi H, Kotani T, Kusakari S, Ishikawa O, Matozaki T. Requirement of SIRPα for protective immunity against Leishmania major Biochem Biophys Res Commun 401, 385-389, 2010 [PubMed]
Saito Y, Iwamura H, Kaneko T, Ohnishi H, Murata Y, Okazawa H, Kanazawa Y, Sato-Hashimoto M, Kobayashi H, Oldenborg P-A, Naito M, Kaneko Y, Nojima Y, Matozaki T. Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues Blood 116, 3517-3525, 2010 [PubMed]
Ohnishi H, Murata T, Kusakari S, Hayashi Y, Takao K, Maruyama T, Ago Y, Koda K, Jin F-J, Okawa K, Oldenborg P-A, Okazawa H, Murata Y, Furuya N, Matsuda T, Miyakawa T, Matozaki T. Stress-evoked tyrosine phosphoryaltion of signal regulatory protein α regulates behavioral immobility in the forced swim test J Neurosci 30, 10472-10483, 2010 [PubMed]
Matozaki T, Murata Y, Mori M, Kotani T, Okazawa H, Ohnishi H. Expression, localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals Cell Signal 22, 1811-1817, 2010 [PubMed]
Murata Y, Mori M, Kotani T, Supriatna, Y, Okazawa H, Kusakari S, Saito Y, Ohnishi H, Matozaki T. Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn Genes Cells 15, 513-524, 2010 [PubMed]
Mori M, Murata Y, Kotani T, Kusakari S, Ohnishi H, Saito Y, Okazawa H, Ishizuka T, Mori M, Matozaki T. Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins J Cell Physiol 224, 195-204, 2010 [PubMed]
Kotani T, Murata Y, Ohnishi H, Mori M, Kusakari S, Saito Y, Okazawa H, Bixby JL, Matozaki T. Expression of PTPRO in the interneurons of adult mouse olfactory bulb J Comp Neurol 518, 119-136, 2010 [PubMed]
Matozaki T, Murata Y, Saito Y, Okazawa H, Ohnishi H. Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation Cancer Sci. 100, 1786-1793, 2009 [PubMed]
Sadakata H, Okazawa H, Sato T, Supriatna Y, Ohnishi H, Kusakari S, Murata Y, Ito T, Nishiyama U, Minegishi T, Harada A, Matozaki T. SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis Genes Cells 14, 295-308, 2009 [PubMed]
Matozaki T, Murata Y, Okazawa H, Ohnishi H. Functions and molecular mechanisms of the CD47-SIRPα signalling pathway Trends Cell Biol 19, 72-80, 2009 [PubMed]
Motegi S, Okazawa H, Murata Y, Kanazawa Y, Saito Y, Kobayashi H, Ohnishi H, Oldenborg P-A, Ishikawa O, Matozaki T. Essential roles of SHPS-1 in induction of contact hypersensitivity of skin Immunol Lett 121, 52-60, 2008 [PubMed]
Kobayashi M, Ohnishi H, Okazawa H, Murata Y, Hayashi Y, Kobayashi H, Kitamura T, Matozaki T. Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic β-cells and its role in promotion of insulin secretion and protection against diabetes Endocrinology 149, 5662-5669, 2008 [PubMed]
Okuzawa C, Kaneko Y, Murata Y, Miyake A, Saito Y, Okajo J, Tomizawa T, Kaneko Y, Okazawa H, Ohnishi H, Matozaki T, Nojima Y. Resistance to collagen-induced arthritis in SHPS-1 mutant mice Biochem Biophys Res Commun 371, 561-566, 2008 [PubMed]
Kusakari S, Ohnishi H, Jin F-J, Kaneko Y, Murata T, Murata Y, Okazawa H, Matozaki T. Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system J Cell Sci 121, 1213-1223, 2008 [PubMed]
Kaneko Y, Kaneko Y, Ohnishi H, Tomizawa T, Okajo J, Saito Y, Okuzawa C, Murata Y, Okazawa H, Nojima Y, Okamoto K, Matozaki T. Impaired proliferation and Th1 differentiation of CD4+ T cells of SHPS-1 mutant mice Kitakanto Med J 58, 133-139, 2008
Miyake A, Murata Y, Okazawa H, Ikeda H, Niwayama Y, Ohnishi H, Hirata Y, Matozaki T. Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages Genes Cells 13, 209-219, 2008 [PubMed]
Nakaishi A, Hirose M, Yoshimura M, Oneyama C, Saito K, Kuki N, Matsuda M, Honma N, Ohnishi H, Matozaki T, Okada M, Nakagawa A. Structural insight into the specific interaction between murine SHPS-1/SIRPα and its ligand CD47 J Mol Biol 375, 650-660, 2008 [PubMed]
Tomizawa T, Kaneko Y, Kaneko Y, Saito Y, Ohnishi H, Okajo J, Okuzawa C, Ishikawa-Sekigami T, Murata Y, Okazawa H, Okamoto K, Nojima Y, Matozaki T. Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice J Immunol 179, 869-877, 2007 [PubMed]
Okajo J, Kaneko Y, Murata Y, Tomizawa T, Okuzawa C, Saito Y, Kaneko Y, Ishikawa-Sekigami T, Okazawa H, Ohnishi H, Matozaki T, Nojima Y. Regulation by src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of α-Galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells J Immunol 178, 6164-6172, 2007 [PubMed]
Ishikawa-Sekigami T., Kaneko Y., Okazawa H., Tomizawa T., Okajo J., Saito Y., Okuzawa C., Sugawara-Yokoo M., Nishiyama U., Ohnishi H., Matozaki T., Nojima Y. SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages Blood 107, 341-348, 2006 [PubMed]
Ikeda H., Okazawa H, Ohnishi H., Murata T., Oldenborg P.-A., Matozaki T. Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages J. Immunol. 177, 3123-3132, 2006 [PubMed]
Murata T., Ohnishi H., Okazawa H., Murata Y., Kusakari S., Hayashi Y., Miyashita M., Itoh H., Oldenborg P.A., Furuya N., Matozaki T. CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42 J. Neurosci. 26, 12397-12407, 2006 [PubMed]
Ishikawa-Sekigami T., Kaneko Y., Saito Y., Murata Y., Okazawa H., Ohnishi H., Oldenborg P.A., Nojima Y., Matozaki T. Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1 Biochem. Biophys. Res. Commun. 343, 1197-1200, 2006 [PubMed]
Shinohara M., Ohyama N., Murata Y., Okazawa H., Ohnishi H., Ishikawa O., Matozaki T. CD47 regulation of epithelial cell spreading and migration, and its signal transduction Cancer Sci. 97, 889-895, 2006 [PubMed]
Nagata A., Ohnishi H., Yoshimura M., Ogawa A., Ujita S., Adachi H., Okada M., Matozaki T., Nakagawa A. Crystallization and preliminary X-ray analysis of rat SHPS-1 Acta Crystallograph. Sec. F Struct Biol. Cryst. Commun. 62(Pt 3), 189-191, 2006 [PubMed]
Ohnishi H., Kaneko Y., Okazawa H., Miyashita M., Sato R., Hayashi A., Tada K., Nagata S., Takahashi M., Matozaki T. Differential localization of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 and CD47 and its molecular mechanisms in cultured hippocampal neurons J. Neurosci. 25, 2702-2711, 2005 [PubMed]
Okazawa H., Motegi S., Ohyama N., Ohnishi H., Tomizawa T., Kaneko Y., Oldenborg P.A., Ishikawa O., Matozaki T. Negative regulation of phagocytosis in macrophages by the CD47–SHPS-1 system J. Immunol. 174, 2004-2011, 2005 [PubMed]
Ohnishi H., Kobayashi H., Okazawa H., Ohe Y., Tomizawa K., Sato R., Matozaki T. Ectodomain shedding of SHPS-1 and its role in regulation of cell migration. J. Biol. Chem. 279, 27878-27887, 2004 [PubMed]
Hayashi A., Ohnishi H., Okazawa H., Nakazawa S., Ikeda H., Motegi S., Aoki N., Kimura S., Mikuni M., Matozaki T. Positive regulation of phagocytosis by SIRPβ and its signaling mechanism in macrophages. J. Biol. Chem. 279, 29450-29460, 2004 [PubMed]
Miyashita M., Ohnishi H., Okazawa H., Tomonaga H., Hayashi A., Fujimoto T.-T., Furuya N., Matozaki T. Promotion of Neurite and Filopodium Formation by CD47: Roles of integrins, Rac, and Cdc42. Mol. Biol. Cell 15, 3950-3963, 2004 [PubMed]
Murai-Takebe R., Noguchi T., Ogura T., Mikami T., Yanagi K., Inagaki K., Ohnishi H., Matozaki T., Kasuga M. Ubiquitination-mediated regulation of biosynthesis of the adhesion receptor SHPS-1 in response to endoplasmic reticulum stress. J. Biol. Chem. 279, 11616-11625, 2004 [PubMed]
Koga T., Inui M., Inoue K., Kim S., Suematsu A., Kobayashi E., Iwata T., Ohnishi H., Matozaki T., Kodama T., Taniguchi T., Takayanagi H., Takai T. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 424, 758-763, 2004 [PubMed]
Motegi S., Okazawa H., Ohnishi H., Sato R., Kaneko Y., Kobayashi H., Tomizawa K., Ito T., Honma N., Buhring H.J., Ishikawa O., Matozaki T. Role of the CD47-SHPS-1 system in regulation of cell migration. EMBO J. 22, 2634-2644, 2003 [PubMed]
Ito T., Okazawa H., Maruyama K., Tomizawa K., Motegi S., Ohnishi H., Kuwano H., Kosugi A., Matozaki T. Interaction of SAP-1, a transmembrane-type protein tyrosine phosphatase, with the tyrosine kinase Lck: Roles in regulation of T cell function. J. Biol. Chem. 278, 34854-34863, 2003 [PubMed]
Ohe Y., Ohnishi H., Okazawa H., Tomizawa K., Kobayashi H., Okawa K., Matozaki T. Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain. Biochem. Biophys. Res. Commun. 308, 719-725, 2003 [PubMed]
Sato R., Ohnishi H., Kobayashi H., Kiuchi D., Hayashi A., Sakazume-Kaneko Y., Honma N., Okazawa H., Hirata Y., Matozaki T. Regulation of multiple functions of SHPS-1, a transmembrane glycoprotein, by its cytoplasmic region. Biochem. Biophys. Res. Commun. 309, 584-590, 2003 [PubMed]
Takahashi M. and Ohnishi H. Negative regulation of exocytosis at the nerve terminal. Mol. Psychiatry 7(6), 536-537, 2002 [PubMed]
Amino S., Itakura M., Ohnishi H., Tsujimura J., Koizumi S., Takei N., Takahashi M. Nerve growth factor enhances neurotransmitter release from PC12 cells by increasing Ca2+-responsible secretory vesicles through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J. Biochem. (Tokyo) 131, 887-894, 2002 [PubMed]
Ohnishi H., Yamamori S., Ono K., Aoyagi K., Kondo S., Takahashi M. A src family tyrosine kinase inhibits neurotransmitter release from neuronal cells. Proc. Natl. Acad. Sci. U.S.A. 98, 10930-10935, 2001 [PubMed]
Yamasaki S., Nishida K., Hibi M., Sakuma M., Shiina R., Takeuchi A., Ohnishi H., Hirano T., Saito T. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules. J. Biol. Chem. 276, 45175-45183, 2001 [PubMed]
Sano S, Ohnishi H, Kubota M. Gene structure of mouse BIT/SHPS-1. Biochem J 344(Pt3): 667-675, 1999 [PubMed]
Yamada M, Ohnishi H, Sano S, Nakatani A, Ikeuchi T, Hatanaka H. Brain-derived neurotrophic factor stimulates interaction of Shp2 with PI3-K and Grb2 in cultured cerebral cortical neurons. J Neurochem 73(1): 41-49, 1999 [PubMed]
Ohnishi H, Yamada M, Kubota M, Hatanaka H, Sano S. Tyrosine phosphorylation and association of BIT with SHP-2 induced by neurotrophins. J Neurochem 72(4): 1402-1408, 1999 [PubMed]
Sano S., Ohnishi H., Omori A., Hasegawa J., Kubota M. BIT, an immune antigen receptor-like molecule in the brain. FEBS Lett 411(2-3): 327-334, 1997 [PubMed]
Yamada M., Ohnishi H., Sano S., Nakatani A., Ikeuchi T., Hatanaka H. Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons. J Biol Chem 272(48): 30334-30339, 1997 [PubMed]
Ohnishi H., Kubota M., Sano S. BIT (Bit) maps to mouse chromosome 2. Genomics 1997; 40(3): 504-506 [PubMed]
Ohnishi H., Sato K., Ohtake A., Kubota M., Sano S. Activation of protein tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule. J Biol Chem 271(41): 25569-25574, 1996 [PubMed]
Ohnishi H., Matsumoto H., Sakai H., Ohta T. Functional roles of Trp337 and Glu632 in Clostridium glucoamylase, as determined by chemical modification, mutagenesis, and the stopped-flow method. J Biol Chem 269(5): 3503-3510, 1994 [PubMed]
Ohnishi H., Kitamura H., Minowa T., Sakai H., Ohta T. Molecular cloning of a glucoamylase gene from a thermophilic Clostridium and kinetics of the cloned enzyme. Eur J Biochem 207(2): 413-418, 1992 [PubMed]
Ohnishi H., Sakai H., Ohta T. Purification and some properties of glucoamylase from Clostridium sp. G0005. Agric Biol Chem 55: 1901-1902, 1991 [J-STAGE]
Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, 3-39-22 Showa-machi, Maebashi, Gunma 371-8514, JAPAN Tel/Fax: +81-27-220-8978 E-mail: ohnishih@gunma-u.ac.jp
